Peer Reviewed Publications

Frias-Lopez, J. Targeting specific bacteria in the oral microbiome. Trends in Microbiology. 24 July 2015. View

Guo L, McLeanb JS, Yang Y, Eckert R, Kaplan CW, Kyme P, Sheikh O, Varnum B, Lux R, Shi W, He X. A precision guided antimicrobial peptide as a targeted modulator of human microbial ecology. The Proceedings of the National Academy of Sciences(PNAS) of the United States of America 2015 ; published ahead of print June 1, 2015, doi:10.1073/pnas.1506207112. View

Eckert R, Sullivan R, Shi W. Targeted antimicrobial treatment to re-establish a healthy microbioal flora for long-term protection. Advances in Dental Research, 2012 September; 24(2):94-97.  View

Yarbrough DK, Eckert R, He J, Hagerman E, Qi F, Lux R, Wu B, Anderson MH, Shi W. Rapid probing of biological surfaces with a sparse-matrix peptide library. PLoS ONE, 2011 August;6(8): e23551. View

Sullivan R, Santarpia P, Lavender S, Gittins E, Liu Z, Anderson MH, He J, Shi W, Eckert R. Clinical efficacy of a specifically targeted antimicrobial peptide mouth rinse: Targeted elimination of Streptococcus mutans and prevention of demineralization. Caries Research 2011;45(5):415-428. View

Kaplan CW, Sim JH, Shah KR, Kolesnikova-Kaplan A, Shi W, Eckert R. Selective membrane disruption: Mode of action of C16G2, a specifically targeted antimicrobial peptide. Antimicrob Agents Chemother, 2011 Jul; 55:3446-3452. View

He J, Yarbrough DK, Kreth J, Anderson MH, Shi W, Eckert, R. A systematic approach to optimizing specifically-targeted antimicrobial peptides against Streptococcus mutans. Antimicrob Agents Chemother, 2010 May;54(5):2143-51. Epub 2010 Mar 8. View

Li L, Guo LH, Lux R, Eckert R, Yarbrough DK, He J, Anderson M, Shi W. Targeted antimicrobial therapy against Streptococcus mutans establishes protective non-cariogenic oral biofilms and reduces subsequent infection. International Journal of Oral Science, 2010 April;1(2):66-73. View

Li L, He J, Eckert R, Yarbrough D, Lux R, Anderson M, Shi W. Design and characterization of an acid-activated antimicrobial peptide. Chemical Biology & Drug Design, 2010 Jan;75(1):127-32. View

He J, Anderson M, Shi W, Eckert R. Design and activity of a ‘dual-targeted’ antimicrobial peptide. International Journal of Antimicrobial Agents, 2009 Jun;33(6):532-7. View

He J, Eckert R, Pharm T, Simanian MD, Hu C, Yarbrough DK, Qi F, Anderson MH, Shi W. Novel synthetic antimicrobial peptides against Streptococcus mutans. Antimicrob Agents Chemother, 2007 Apr;51(4):1351-8. Epub 2007 Feb 12. View

Eckert R, He J, Yarbrough DK, Qi F, Anderson MH, Shi W. Targeted killing of Streptococcus mutans by a pheromone-guided “smart” antimicrobial peptide. Antimicrob Agents Chemother, 2006 Nov;50(11):3651-7. View

Yarbrough DK, Hagerman E, Eckert R, He J, Choi H, Cao N, Le K, Hedger J, Qi F, Anderson M, Rutherford B, Wu B, Tetradis S, Shi W. Specific binding and mineralization of calcified surfaces by small peptides. Calcified Tissue International, 2010 Jan;86(1):58-66. View